Status:
COMPLETED
The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts"
Lead Sponsor:
Massachusetts General Hospital
Collaborating Sponsors:
Health Resources in Action, Inc.
Conditions:
Obsessive-Compulsive Disorder
Generalized Anxiety Disorder
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The investigators are examining whether difficulties with cognitive control (i.e., the ability to stop one's thought process and shift attention) is a common problem across three types of repetitive, ...
Detailed Description
The primary aims of this study are to utilize self-report and behavioral measures to examine whether cognitive control is a common factor across three types of repetitive negative thinking (RNT): obse...
Eligibility Criteria
Inclusion
- Adults (age 18+)
- Intrusive thoughts group: Clinically significant intrusive thought in the domain of obsessions, worries, or depressive ruminations with a score above the clinical mean (≥ 37) on the trait repetitive negative thinking measure (Perseverative Thinking Questionnaire, PTQ)
- Non-psychiatric control (NPC) group: A score 1 SD below the community mean (≤ 15) on the trait repetitive negative thinking measure (PTQ)
- Sufficient fluency of English to understand study procedures and questionnaires
- Ability to provide informed consent.
- Comfortable and capable of using a computer and completing reaction-time tasks.
Exclusion
- Acute psychosis, mania, or suicidality
- Diagnosis of post-traumatic stress disorder (PTSD; in order to preserve diagnostic clarity of the domains of intrusive thoughts under investigation)
- Serious neurological disorder or impairment (e.g., brain damage, blindness), attention deficit hyperactivity disorder (ADHD), intellectual disability, or autism.
Key Trial Info
Start Date :
May 18 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 6 2020
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT03414619
Start Date
May 18 2018
End Date
March 6 2020
Last Update
March 18 2020
Active Locations (1)
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1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114