Status:
COMPLETED
Management of Malignant Pleural Effusions Using an Indwelling Tunneled Pleural Catheter and Non-Vacuum Collection System
Lead Sponsor:
Washington University School of Medicine
Collaborating Sponsors:
Merit Medical Systems, Inc.
Conditions:
Malignant Pleural Effusion
Eligibility:
All Genders
18+ years
Brief Summary
In this study, the investigators will collect data on patients who are using the Aspira system as part of their clinical care for the management of recurrent pleural effusion. Data will be collected o...
Eligibility Criteria
Inclusion
- Male or female, at least 18 years of age, inclusive
- Subject has a symptomatic malignant pleural effusion requiring intervention. For an effusion to be defined as malignant, at least one of the following must be true
- There is cytological confirmation of pleural malignancy
- The effusion is an exudate (per Light's criteria Pleural fluid protein/Serum protein \>0.5, Pleural fluid LDH/Serum LDH \>0.6, or Pleural fluid LDH \>2/3 the upper limit of normal) in the context of histocytologically proven malignancy elsewhere, with no other clear cause for fluid identified
- Subject is able to provide informed consent
- Subject has sufficient pleural fluid to allow safe insertion of an indwelling tunneled pleural catheter as determined by the PI
- Subject is able to perform home drainage of the pleural effusion or has sufficient resources (family member, caregiver, home health).
Exclusion
- Subject is pregnant
- Subject has evidence, in the opinion of the PI, of either ongoing systemic or pleural infection
- Subjects with uncorrected coagulopathy
Key Trial Info
Start Date :
July 9 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 15 2024
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03414905
Start Date
July 9 2018
End Date
February 15 2024
Last Update
February 20 2024
Active Locations (1)
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1
Washington University School of Medicine
St Louis, Missouri, United States, 63110