Status:
UNKNOWN
Left Ventricular Septal Pacing: Potential Application for Cardiac Resynchronization Therapy
Lead Sponsor:
Maastricht University Medical Center
Conditions:
Heart Failure
Cardiac Resynchronization Therapy
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
In cardiac resynchronization therapy (CRT), biventricular pacing is performed by pacing the right ventricle (RV) and epicardium of the left ventricular (LV) postero-lateral wall. A significant proport...
Detailed Description
Cardiac pump function depends on physiological electrical activation of the ventricles. This normal activation is disturbed during artificial electrical stimulation (pacing) of the right ventricle (RV...
Eligibility Criteria
Inclusion
- Chronic heart failure with NYHA functional class II-IV
- Left ventricular ejection fraction (LVEF) \< 35%
- LBBB and QRS duration ≥ 130 ms or non-LBBB and QRS duration ≥ 150 ms
- In sinus rhythm
- Optimal pharmacological therapy
Exclusion
- Persistent atrial fibrillation
- ≥ 2 premature ventricular complexes on standard 12-lead electrocardiogram (ECG)
- Age \< 18 years
- Incapable of giving informed consent
- Moderate to severe aortic valve stenosis
- Peripheral vascular disease
Key Trial Info
Start Date :
November 23 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 23 2020
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03415945
Start Date
November 23 2017
End Date
May 23 2020
Last Update
February 12 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Maastricht University Medical Center
Maastricht, Limburg, Netherlands, 6229 HX