Status:

COMPLETED

Effect of Propolis or Metformin Administration on Glycemic Control in Patients With Type 2 Diabetes Mellitus

Lead Sponsor:

University of Guadalajara

Conditions:

Diabetes Mellitus, Type 2

Eligibility:

All Genders

30-60 years

Phase:

PHASE2

Brief Summary

The aim of this study was to evaluate the effect of propolis or metformin on glycemic control in patients with type 2 diabetes mellitus without pharmacological treatment. All patients received for 12...

Detailed Description

A randomized, double-blind, placebo-controlled clinical trial of three pharmacological groups was carried out, with the participation of 36 patients with type 2 Diabetes Mellitus without pharmacologic...

Eligibility Criteria

Inclusion

  • Patients both sexes
  • Age between 30 and 60 years
  • Mild to moderate physical activity
  • Stable body weight for at least 12 weeks prior to the study
  • BMI 25.0 - 34.9 kg/m2
  • Diabetes mellitus type 2 of recent diagnosis without pharmacological treatment, with one of the following criteria (fasting blood glucose levels \>126 mg/dl; or postprandial blood glucose levels after an oral glucose tolerance test with 75 of oral glucose \>200 mg/dl
  • Informed consent signed

Exclusion

  • Women with confirmed or suspected pregnancy
  • Women under lactation and/or puerperium
  • Previous treatment for glucose
  • Fasting glucose ≥250 mg/dL
  • Known uncontrolled renal, hepatic, heart or thyroid diseased
  • Hypersensibility to ingredients of intervention
  • Known allergies to bee stings or their derived products
  • Triglycerides ≥500 mg/dL
  • Total cholesterol ≥240 mg/dL

Key Trial Info

Start Date :

January 30 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 20 2019

Estimated Enrollment :

36 Patients enrolled

Trial Details

Trial ID

NCT03416127

Start Date

January 30 2018

End Date

December 20 2019

Last Update

November 7 2022

Active Locations (1)

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Intstituto de Terapeútica Experimental y Clínica. Centro Universitario de Ciencias de la Salud. Universidad de Guadalajara

Guadalajara, Jalisco, Mexico, 44340