Status:
COMPLETED
Meat-based Versus Pesco-vegetarian Diet and Colorectal Cancer
Lead Sponsor:
Azienda Ospedaliero-Universitaria Careggi
Conditions:
Nutrition Aspect of Cancer
Diet Modification
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
Colorectal cancer (CRC) is strongly affected by diet, with red and processed meat increasing risk. To understand the role of microbiome in this phenomenon and to identify specific microbiome/metabolom...
Detailed Description
Colorectal cancer (CRC) is the second leading cause of cancer death in Europe. The geographical variation of incidence demonstrates how environmental factors, chiefly dietary habits, play a major role...
Eligibility Criteria
Inclusion
- clinically healthy (both sexes)
- age \>18 years and ≤ 50 years.
- The study population will be selected with an age ranging from 18 to 50 years because after 50 years the risk for CRC shows a significant increase in incidence. In fact, more than 90% of the people diagnosed with the disease are older than 50, with the average age at the time of diagnosis being 64 (Amersi et al., 2005). With respect to gender, its role in the development of colorectal cancer remains unclear (Amersi et al., 2005).
Exclusion
- Presence of current illness or unstable conditions
- Current or recent (past 2 months) use of antibiotics or probiotics
- Pregnancy or intention to become pregnant in the next 12 months or lactation
- Current smoking habit
- Current or recent (past 2 months) adoption of a vegetarian diet
Key Trial Info
Start Date :
June 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 30 2021
Estimated Enrollment :
103 Patients enrolled
Trial Details
Trial ID
NCT03416777
Start Date
June 1 2019
End Date
April 30 2021
Last Update
July 30 2021
Active Locations (1)
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1
Unit of Clinical Nutrition, University Hospital of Careggi
Florence, Italy, 50134