Status:
RECRUITING
Accelerated iTBS for Post Partum Depression
Lead Sponsor:
Medical University of South Carolina
Conditions:
Post Partum Depression
Eligibility:
FEMALE
18-50 years
Phase:
NA
Brief Summary
Study 1: The investigators are studying the feasibility and tolerability of 10x/day intermittent theta burst (excitatory) transcranial magnetic stimulation to the left dorsolateral prefrontal cortex o...
Detailed Description
Study 1: This is an open-label study designed to investigate the feasibility and tolerability of a novel TMS treatment protocol to treat depression in women with post-partum depression. It is known th...
Eligibility Criteria
Inclusion
- Participants must be able to provide informed consent and function at an intellectual level sufficient to allow accurate completion of all assessment instruments.
- Participants must be over the age of 18.
- Participants must meet criteria for post-partum depression: a) onset of symptoms in the first year postpartum
- Participants must have a HRSD17 greater than or equal to 14 at baseline.
Exclusion
- Participants must not be pregnant.
- Participants must not meet moderate or severe use disorder of any substance with the exception of Tobacco Use Disorder.
- Participants must not have current psychotic symptoms.
- Participants must not have a history of dementia or other cognitive impairment.
- Participants must not have active suicidal ideation requiring hospitalization or a suicide attempt within the past 3 months.
- Participants must not have any contraindications to receiving rTMS (e.g. metal implanted above the neck, history of seizure, any known brain lesion).
- Participants must not have any unstable general medical conditions.
- Participants must not have had eclampsia during pregnancy.
Key Trial Info
Start Date :
January 24 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 30 2027
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT03417960
Start Date
January 24 2018
End Date
August 30 2027
Last Update
September 11 2025
Active Locations (1)
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1
Medical University of South Carolina
Charleston, South Carolina, United States, 29425