Status:
COMPLETED
Comparison of Cytokine Profiles in Aqueous Humor of Patients With Age Related Macular Degeneration (AMD)
Lead Sponsor:
Hospices Civils de Lyon
Conditions:
Macular Degeneration, Age-Related
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
Age-related macular degeneration (AMD) affects 2 million people in France. It characterized by progressive degeneration of the central area of the retina allowing detailed vision. It is the main cause...
Eligibility Criteria
Inclusion
- • GENERAL CRITERIA
- Man or woman with age over 60 years,
- Informed, written and signed consent by the patient and the investigator (no later than the day of inclusion) and before any investigation required by the research,
- Patient affiliated with social security,
- Patient willing and able to return to all clinical visits to the study and complete all related procedures.
- • SPECIFIC CRITERIA
- Patient who need a cataract surgery,
- Patient presenting in both eyes:
- the same type of AMD defined according to the international AREDS study modified (Ferris et al., 2013) no other ophthalmological pathology (control group).
Exclusion
- • GENERAL CRITERIA
- Major patient under tutorship or curatorship or unable to express consent,
- Person deprived of liberty,
- Patient participating in an ongoing clinical trial during the inclusion visit,
- • SPECIFIC CRITERIA
- Patient with chronic ophthalmic pathologies other than cataract and AMD defined in the modified international AREDS study included in the eye (Ferris et al., 2013),
- Patient who participated in a clinical trial of an experimental drug for atrophic AMD,
- Patient taking systemically drugs with immunomodulatory action: immunosuppressants, immunomodulators, chemotherapy or corticosteroids,
- Patient with systemic diseases modifying his immune status,
- Patient with a history of diabetes,
- Patient who received an anti-inflammatory eye treatment in both eyes in the 6 months preceding the surgery,
- Patient having dynamic phototherapy on the included eye.
Key Trial Info
Start Date :
November 22 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 8 2020
Estimated Enrollment :
82 Patients enrolled
Trial Details
Trial ID
NCT03418220
Start Date
November 22 2017
End Date
September 8 2020
Last Update
December 5 2025
Active Locations (1)
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1
Hôpital de la Croix-Rousse
Lyon, France, 69004