Status:

COMPLETED

Non-invasive Diagnostic for Assessing Elevated Intracranial Pressure

Lead Sponsor:

Oculogica, Inc.

Conditions:

Intracranial Pressure Increase

Eligibility:

All Genders

4-70 years

Brief Summary

The study is a prospective, multi-center, non-randomized, open label observational study. The objective of this study is to compare the accuracy of the EyeBOX to a clinical diagnosis of abnormal ICP a...

Eligibility Criteria

Inclusion

  • Provide written informed consent.
  • Require placement of an ICP monitor or ventriculostomy catheter for clinical purposes.
  • Be between the ages of 4 and 70 years old.
  • Have baseline vision correctable to within 20/500 bilaterally.
  • Have no prior history of ocular dysmotility.
  • Be awake with spontaneous eye opening at the time when eye tracking is performed.

Exclusion

  • Have a prior history of strabismus, diplopia, or palsy of CN-III, IV or VI.
  • Be blind (no light perception), have missing eyes, be unable to open their eyes.
  • Have a prior history of ocular motility dysfunction.
  • Have had extensive prior eye surgery.
  • Have any physical or mental injury or baseline disability rendering task completion difficult.
  • Be intoxicated or have blood alcohol level greater than 0.2.
  • Be a prisoner or in the company of a police officer or law enforcement officer pending arrest.

Key Trial Info

Start Date :

May 10 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 10 2023

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT03418753

Start Date

May 10 2018

End Date

May 10 2023

Last Update

September 7 2023

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Johns Hopkins Hospital

Baltimore, Maryland, United States, 21287

2

Mayo Clinic

Rochester, Minnesota, United States, 55905

3

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104