Status:
UNKNOWN
The Relationship Between Right-to-left Shunt and Brain White Matter Lesions in Patients With Migraine
Lead Sponsor:
The First Hospital of Jilin University
Collaborating Sponsors:
National Natural Science Foundation of China
Conditions:
White Matter Disease
Right-to-left Shunt
Eligibility:
All Genders
18-50 years
Brief Summary
The purpose of the study is to evaluate the prevalence of white matter lesions in Chinese migraineurs with and without right-to-left shunt. The aim is to study the relationship among right-to-left shu...
Detailed Description
This is a prospective multicenter study of Chinese population. Participants (normal individuals without migraine and migraineurs) are included after standardized diagnostic procedures (TCD and migrain...
Eligibility Criteria
Inclusion
- patients who fulfilled the criteria for migraine according to the International Classification of Headache Disorders III-beta were included.
- healthy volunteers without a history of migraine were included as controls.
Exclusion
- Subjects were excluded from the study if they had severe arterial stenosis, an insufficient temporal window, inadequate cubital venous access, and/or were unable to perform the Valsalva manoeuvre (VM) because of severe heart or lung disease.
Key Trial Info
Start Date :
June 15 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 30 2020
Estimated Enrollment :
1500 Patients enrolled
Trial Details
Trial ID
NCT03418766
Start Date
June 15 2018
End Date
December 30 2020
Last Update
July 23 2020
Active Locations (1)
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1
First hospital of Jilin Uni
Changchun, Jilin, China, 130000