Status:
COMPLETED
Transformation Into Small Cell Lung Cancer : a Mode of Resistance to Treatment
Lead Sponsor:
University Hospital, Grenoble
Conditions:
Small Cell Lung Cancer
Eligibility:
All Genders
Brief Summary
The discovery of oncogenic mutations and the use of targeted therapies have transformed the management of certain tumors. Thus 12 to 15% of bronchial adenocarcinomas (AD) carry mutations of EGFR and r...
Detailed Description
An international multicentric retrospective collection of cases was performed between 2005 and 2017. A global e-mailing to a network of thoracic oncology centers in France and Italy called for the sel...
Eligibility Criteria
Inclusion
- Patient with no history of small cell cancer or Neuroendocrine cancer
- Patients with non-small cell lung cancer at baseline, stage IIIB or IV
- Transformation during treatment of non small cell lung cancer, in small cell cancer proven by biopsy
Exclusion
- History of small cell cancer or Neuroendocrine cancer
- Absence of histological evidence of the transformation into small cell lung cancer after treatment of non small cell lung cancer
- Patients with non-small cell lung cancer at initial biopsy, stage I, II, IIIA
Key Trial Info
Start Date :
February 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 1 2017
Estimated Enrollment :
62 Patients enrolled
Trial Details
Trial ID
NCT03419286
Start Date
February 1 2016
End Date
November 1 2017
Last Update
February 1 2018
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