Status:
UNKNOWN
Microbiota is Related With Increasing Infection Rates After Splenectomy
Lead Sponsor:
First Affiliated Hospital of Harbin Medical University
Conditions:
Gut Microbiota
Spleen Injury
Eligibility:
All Genders
18+ years
Brief Summary
Studies has shown an increasingly infection rate after splenectomy, and there is a potential correlation between microbiota and immune system. investigators suppose that increasingly infection can be ...
Detailed Description
The spleen is crucial in regulating immune homoeostasis through its ability to link innate and adaptive immunity and to protect against infections. Asplenia refers to the absence of the spleen, a diso...
Eligibility Criteria
Inclusion
- All the patients underwent an total splenectomy in the First Affiliated Hospital of Harbin Medical University from January 1st, 2015 to May 1st, 2017. Each participant provided a fresh stool sample in hospital when following-up.
Exclusion
- Use antibiotics and probiotics 3 mouth before samples collection.
- Other severe abdomen injury
- Underwent abdomen organ resection surgery
- Other digestive system disease
Key Trial Info
Start Date :
May 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 10 2019
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT03420599
Start Date
May 1 2017
End Date
December 10 2019
Last Update
February 25 2019
Active Locations (1)
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1
First affiliated hospital of Harbin medical university
Harbin, Heilongjiang, China, 150001