Status:
COMPLETED
Drug Order for Rapid Sequence Intubation
Lead Sponsor:
Hennepin Healthcare Research Institute
Conditions:
Acute Respiratory Failure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This is a randomized, blinded trial comparing the order of drug administration for rapid sequence intubation in the Emergency Department.
Detailed Description
Based on data (excluding outliers) from protocol 16-4146, the intubation time with the paralytic and sedative first administered is 86 s, and 93 s, respectively, with a standard deviation of approxima...
Eligibility Criteria
Inclusion
- The patient must be undergoing orotracheal intubation in the Emergency Department
- The patient must be receiving both a sedative and paralytic immediately prior to intubation (i.e. undergoing rapid sequence intubation).
- The patient must be presumed to be 18 years of age or older at the time of enrollment.
Exclusion
- Prisoner or in custody
- Known or suspected to be pregnant, based on the opinion of the attending physician.
- Intubation performed by a physician assistant (this is rarely done in our ED; each physician assistant intubates less than twice per year, so the intubation outcomes would hinge more on their experience rather than drug order).
Key Trial Info
Start Date :
February 5 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 29 2021
Estimated Enrollment :
335 Patients enrolled
Trial Details
Trial ID
NCT03420950
Start Date
February 5 2018
End Date
September 29 2021
Last Update
February 3 2022
Active Locations (1)
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1
Hennepin County Medical Center
Minneapolis, Minnesota, United States, 55415