Status:

COMPLETED

Dietary Phytoestrogens as Risk Factors for Systemic Lupus Erythematosus

Lead Sponsor:

University Hospital, Bordeaux

Conditions:

Lupus Erythematosus

Rheumatoid Arthritis

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

The study aims at determining if dietary phytoestrogens can be risk factors for Systemic Lupus Erythematosus (SLE). Dietary enquiry and phytoestrogens measurements will be performed in blood and urine...

Detailed Description

SLE is a disease occurring in 90% of the cases in pre-menopausal women. The causing factors are largely unknown even though genetic and environmental factors have already been identified. Estrogens, o...

Eligibility Criteria

Inclusion

  • Group : Systemic Lupus Erythematosus :
  • Premenopausal women over 18
  • with acute LEAD flare
  • having given informed consent
  • and being covered by social insurance.
  • Group : Autoimmune diseases :
  • Premenopausal women of matching age with other autoimmune disease,
  • having given informed consent
  • and being covered by social insurance.
  • Healthy controls :
  • Premenopausal women over 18,
  • having given informed consent,
  • and being covered by social insurance.

Exclusion

  • Group Systemic Lupus Erythematosus and group autoimmune diseases
  • Human Immunodeficiency virus (HIV), hepatitis C virus (HCV) or hepatitis C virus (HBV) sero-positivity;
  • pregnant or lactating women;
  • menopausal women;
  • patient in remission of quiescent phase of her pathology;
  • Healthy controls :
  • HIV, HCV or HBV sero-positivity;
  • pregnant or lactating women;
  • menopausal women.

Key Trial Info

Start Date :

November 26 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 26 2023

Estimated Enrollment :

63 Patients enrolled

Trial Details

Trial ID

NCT03421184

Start Date

November 26 2018

End Date

June 26 2023

Last Update

July 7 2023

Active Locations (1)

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1

CHU de Bordeaux - service de médecine interne

Pessac, France