Status:

COMPLETED

A Prospective Multicenter Registry of Patients With Sleep Disordered Breathing Treated With DreamStation BiPAP autoSV.

Lead Sponsor:

Philips Respironics

Conditions:

Central Sleep Apnea

Mixed Sleep Apnea

Eligibility:

All Genders

18-99 years

Brief Summary

This multi-center observational study will prospectively collect data from patients who have an indication for servo ventilation therapy. This registry is intended to characterize the patient populati...

Eligibility Criteria

Inclusion

  • Indication and prescription of PR DS-autoSV
  • Polysomnographic (PSG) or Polygraphic (PG) documentation of sleep-disordered breathing requiring servo ventilation

Exclusion

  • Patients with HFrEF - heart failure and low ejection fraction (EF ≤ 45%) and predominant CSA (\> 50 % of events)
  • Patients not able to receive positive airway pressure support through a mask due to surgical procedure or anatomical condition
  • Chronic conditions with life expectancy \< 1 year
  • Significant chronic obstructive pulmonary disease (COPD) with an FEV1/VC \< 70% (GOLD III)
  • Respiratory insufficiency requiring long-term oxygen therapy
  • Daytime hypercapnia at rest (pCO2 \> 45 mmHg)
  • Cardiac surgery, PCI, myocardial infarction, unstable angina, within 12 weeks prior to enrolment
  • Cardiac resynchronization or pacemaker implantation within the last 6 months
  • Untreated or therapy refractory Restless legs-Syndrome (RLS)

Key Trial Info

Start Date :

January 25 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 20 2023

Estimated Enrollment :

129 Patients enrolled

Trial Details

Trial ID

NCT03421704

Start Date

January 25 2018

End Date

April 20 2023

Last Update

October 2 2023

Active Locations (9)

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Page 1 of 3 (9 locations)

1

Universitätsklinikum der Ruhr-Universität Bochum

Bad Oeynhausen, Germany

2

Charité

Berlin, Germany, 10117

3

Klinik Donaustauf

Donaustauf, Germany

4

Helios Klinik Hagen Ambrok

Hagen, Germany, 6058091