Status:
COMPLETED
Non-invasive Stimulation of Brain Networks and Cognition in Alzheimer's Disease and Frontotemporal Dementia
Lead Sponsor:
IRCCS Centro San Giovanni di Dio Fatebenefratelli
Conditions:
Alzheimer's Disease
Frontotemporal Dementia, Behavioral Variant
Eligibility:
All Genders
50-85 years
Phase:
NA
Brief Summary
This pilot study aims to test clinical and connectivity changes following non-invasive stimulation of disease-specific networks in Alzheimer's disease (AD) and behavioral variant frontotemporal dement...
Eligibility Criteria
Inclusion
- Diagnosis of AD or bvFTD according to current clinical criteria (Albert et al., 2011; Rascovsky et al., 2011)
- Ability to provide written informed consent
- Availability of a collateral source
Exclusion
- Moderate/severe dementia
- Presence of any medical or psychiatric illness that could interfere in completing assessments
- Exclusion Criteria for MRI and tDCS:
- metal implants, pace-makers, prosthetic heart valves
- claustrophobia
- history of epilepsy
- pregnancy
- Exclusion Criteria for controls:
- Current or past history of clinical, neurological, or psychiatric conditions that could interfere with the assessment (e.g., transient ischemic attack, ictus, head trauma, epilepsy, multiple sclerosis, neuropathy, mood disorders, substance abuse)
Key Trial Info
Start Date :
June 8 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 3 2018
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT03422250
Start Date
June 8 2015
End Date
November 3 2018
Last Update
May 19 2021
Active Locations (1)
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1
IRCCS Centro San Giovanni di Dio Fatebenefratelli
Brescia, Italy, 25125