Status:

RECRUITING

Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer

Lead Sponsor:

M.D. Anderson Cancer Center

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Lung Carcinoma

Malignant Respiratory Tract Neoplasm

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This pilot phase I/II trial studies how well a continuous positive airway pressure device or deep inspiration breath hold works in reducing tumor movement in patients undergoing stereotactic body radi...

Detailed Description

PRIMARY OBJECTIVES: I. To compare the two methods of tumor motion management, continuous positive airway pressure (CPAP) and deep inspiration breath hold (DIBH) and to estimate the decrease in tumor ...

Eligibility Criteria

Inclusion

  • The patient will receive stereotactic body radiotherapy in the Thoracic Radiation Oncolcogy Service at MD Anderson.

Exclusion

  • The patient has a contra-indication for using a CPAP device.
  • The patient has not signed a study-specific informed consent for this study.
  • The patient is uncooperative.
  • The patient has reduced consciousness.
  • The patient has sustained trauma or burns to the face.
  • The patient has undergone any facial, esophageal, gastric or sinus surgery within the last 3 months.
  • The patient has idiopathic pulmonary fibrosis (IPF) as documented in their medical history.
  • Adults who are unable to consent, individuals who are not yet adults, pregnant women and prisoners will be excluded from this study.

Key Trial Info

Start Date :

March 16 2018

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 31 2028

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT03422302

Start Date

March 16 2018

End Date

May 31 2028

Last Update

August 26 2025

Active Locations (1)

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1

M D Anderson Cancer Center

Houston, Texas, United States, 77030