Status:

WITHDRAWN

TIPS or Anticoagulation in Portal Vein Thrombosis

Lead Sponsor:

Insel Gruppe AG, University Hospital Bern

Conditions:

Thrombosis Portal Vein

Eligibility:

All Genders

Phase:

PHASE3

Brief Summary

The PROGRESS is an investigator-initiated, multicentre, randomized, trial comparing anticoagulation, which is the currently most frequently used treatment, alone, versus transjugular intrahepatic port...

Eligibility Criteria

Inclusion

  • Recent complete thrombosis of the extrahepatic portal vein either with or without the involvement of intrahepatic branches and with or without involvement of splenic vein and superior mesenteric vein
  • Written informed consent

Exclusion

  • Malignant Portal Vein thrombosis (neoplastic invasion)
  • Intraabdominal malignancy
  • Chronic diseases limiting life expectancy in the short term (6 months)
  • Liver transplantation
  • Unwillingness to participate
  • Contraindications to TIPS (including past or present hepatic encephalopathy Grade ≥2)
  • Child-Pugh-Turcotte score 11 or more points in patients with advanced chronic liver disease-

Key Trial Info

Start Date :

August 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 31 2021

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT03422419

Start Date

August 1 2018

End Date

July 31 2021

Last Update

November 1 2018

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