Status:
COMPLETED
The Effect of Sumatriptan and Placebo Injection on Cilostazol Induced Headache
Lead Sponsor:
Danish Headache Center
Conditions:
Migraine
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
To develop a pragmatic migraine model the investigators will induce headache in patients with migraine without aura with a phosphodiesterase inhibitor (cilostazol). If the headache responds to sumatri...
Detailed Description
There remains a great need for more effective anti-migraine drugs with fewer side effects. Human experimental models are valuable in early phase development of new anti-migraine drugs but useful model...
Eligibility Criteria
Inclusion
- Migraine patients who meet IHS criteria for migraine with or without aura of both sexes
- 18-70 years
- 45-95 kg.
Exclusion
- Any other type of headache then migraine without aura (except episodic tension-type headache \< 1 day per week)
- Serious somatic or psychiatric disease
- Pregnancy
- Intake of daily medication (except oral contraceptives)
- Triptan non-responders
Key Trial Info
Start Date :
November 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2018
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03422796
Start Date
November 1 2017
End Date
September 1 2018
Last Update
January 29 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Rigshospitalet Glostrup
Glostrup Municipality, Denmark, 2600