Status:
COMPLETED
Brainstem Dysfunction Involvement in the Pathogenesis of Pierre Robin Sequence
Lead Sponsor:
Hospices Civils de Lyon
Conditions:
Pierre Robin Sequence
Brainstem Dysfunction
Eligibility:
All Genders
1-2 years
Phase:
NA
Brief Summary
Introduction Pierre Robin Sequence, PRS, incidence is about one hundred births per year in France. The main neonatal clinical manifestations are secondary to airway obstruction and food difficulties r...
Eligibility Criteria
Inclusion
- Inclusion Criteria for the group 1
- \- infants with PRS
- Inclusion Criteria for the group 2 - infant with isolated airway obstruction
- Inclusion Criteria for the group 3
- \- healthy infant : siblings of sudden unexpected death of the infant or with any known pathology
- Inclusion Criteria for the 3 groups
- During one hospitalization or program for one hospitalization
- Parental consent
- Social safety affiliation
- Exclusion Criteria:
- Birth before 37 SA
- Neonatal complication
- Group 2 only: AWO with neurological disease including brainstem dysfunction
- Group 3 only : AWO, ENT disease or syndromic disease, neurological disease including brainstem dysfunction, Intra uterine growth retardation
Exclusion
Key Trial Info
Start Date :
May 24 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 23 2023
Estimated Enrollment :
113 Patients enrolled
Trial Details
Trial ID
NCT03423017
Start Date
May 24 2018
End Date
March 23 2023
Last Update
January 10 2024
Active Locations (2)
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1
Hopital Femme Mère Enfant
Bron, France, 69500
2
APHP-Necker
Paris, France, 75015 Paris