Status:
COMPLETED
Oxytocin, Trauma Disclosure and Intrusions
Lead Sponsor:
University Hospital, Bonn
Conditions:
Healthy
Eligibility:
FEMALE
18-40 years
Phase:
PHASE1
Brief Summary
Severe traumatic experiences such as falling victim to assault, torture, or rape have deleterious effects. Clinical manifestations include intrusions, avoidance behavior, and hyperarousal, which are a...
Detailed Description
Participants will be exposed to an experimental trauma (i.e. a highly aversive movie) at days 1 and 4 of the study. After the first experimental trauma and after the first functional magnetic resonanc...
Eligibility Criteria
Inclusion
- Healthy female volunteers
- Right-handed
Exclusion
- Current or past psychiatric disease
- Current or past physical illness
- Psychoactive medication
- Hormonal contraception
- MRI contraindication (e.g. metal in body, claustrophobia)
Key Trial Info
Start Date :
June 1 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 18 2017
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT03425929
Start Date
June 1 2016
End Date
March 18 2017
Last Update
February 8 2018
Active Locations (1)
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1
Department of Psychiatry, University of Bonn
Bonn, Germany, 53105