Status:
UNKNOWN
Glucose Absorption and Gut Hormone Secretion After Gastric Bypass
Lead Sponsor:
Hvidovre University Hospital
Conditions:
Overweight
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
To investigate the impact of canagliflozin on secretion of gut hormones, in particular glucagon-like peptide 1 (GLP-1) in gastric bypass operated patients.
Detailed Description
Glucose is a potent stimulus for GLP-1 secretion after gastric bypass surgery and the SGLT-1 transporter appears to be crucial for this response. The study will investigate the effects of SGLT-1/SGLT-...
Eligibility Criteria
Inclusion
- •Uncomplicated gastric bypass surgery performed minimum 12 months prior to study
Exclusion
- Type 1 or 2 diabetes mellitus prior to or after gastric bypass surgery
- Pregnancy or breastfeeding
- Haemoglobin levels below 6,5 mM
Key Trial Info
Start Date :
February 8 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2019
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03426956
Start Date
February 8 2018
End Date
May 1 2019
Last Update
February 9 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Dept. of Endocrinology
Hvidovre, Denmark, 2650