Status:

COMPLETED

Small and Steatotic Hepatocellular Carcinoma

Lead Sponsor:

University Hospital, Montpellier

Conditions:

HCC

Eligibility:

All Genders

18+ years

Brief Summary

Percutaneous thermoablation in an effective local curative treatment in patients with cirrhosis and HCC smaller than 3 cm in diameter (BCLC 0-A). Around 30% of HCC patients referred for percutaneous ...

Detailed Description

We performed 412 percutaneous thermoablations on 238 patients for HCC between January 2015 and November 2019. All thermoablation procedures were performed percutaneously under ultrasound or CT guidan...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • HCC according to histological examination or Barcelona criteria
  • BCLC0 or A
  • Measurable targets according to mRECIST v1.1
  • Child A or B7 cirrhosis
  • HCC \< 4 cm, \< 3 nodules, Age ≥ 18 years
  • No extrahepatic metastasis, no vascular invasion
  • Performance status 0 or 1
  • Thrombocytes ≥ 50 000/mm3, TP \> 50%
  • Exclusion criteria:
  • Follow-up \< 1month
  • Lobar/main portal venous thrombus
  • Abundant ascites
  • Antecedent of bilio-digestive anastomosis or endoscopic sphincterotomy
  • Combined treatment with embolization or chemo-embolization

Exclusion

    Key Trial Info

    Start Date :

    January 1 2015

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    December 30 2019

    Estimated Enrollment :

    238 Patients enrolled

    Trial Details

    Trial ID

    NCT03428321

    Start Date

    January 1 2015

    End Date

    December 30 2019

    Last Update

    May 6 2020

    Active Locations (1)

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    Uhmontpellier

    Montpellier, France, 34295