Status:

COMPLETED

Register Study of the Neoadjuvanten Treatment by Patients With Rectumcarcinoma

Lead Sponsor:

University Hospital Tuebingen

Conditions:

Feasibilitystudy

Eligibility:

All Genders

18-80 years

Brief Summary

goal of this study is to check the effecivity, feasibility and toxicity of the chemoradiotherapy and hyperthermia

Detailed Description

Radiation: 5x1,8Gy until 50,4 Gy Hyperthermia: 2x/week Chemotherapy: neoadjuvant= day 1-5 and day 29-33 5FU 1000mg/m2 adjuvant = 4 Cycles 5FU 500mg/m2 all 4 weeks

Eligibility Criteria

Inclusion

  • adenocarcinoma until 10 cm until ano UICC II+III 18-80 years old ECOG PS 0-2 Informed Consent

Exclusion

  • cardiac insufficiency last 6 month heartattack nodal AV pressure III° hip prothesis cardiac pacemaker others contraindikations against the therapie radiation of pelvis chronic gestrointestinal desaese gestation or lactation previous radiotion pelvis previous Chemotherapie second carcinoma beside baslioma infiltation in analarea

Key Trial Info

Start Date :

August 1 2012

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 31 2017

Estimated Enrollment :

78 Patients enrolled

Trial Details

Trial ID

NCT03428867

Start Date

August 1 2012

End Date

July 31 2017

Last Update

February 13 2018

Active Locations (1)

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1

University Hospital Tuebingen

Tübingen, Baden-Wurttemberg, Germany, 72070