Status:

UNKNOWN

Respiratory Microbiome and COPD Exacerbations (RESMECOPD)

Lead Sponsor:

Corporacion Parc Tauli

Collaborating Sponsors:

Hospital de Sant Pau

Hospital Clinic of Barcelona

Conditions:

Pulmonary Disease, Chronic Obstructive

Exacerbation COPD

Eligibility:

All Genders

40-75 years

Brief Summary

The global objective of this coordinated project is to test the following hypotheses: 1) the lung microbiome in chronic obstructive pulmonary disease (COPD) is different in patients suffering from fre...

Eligibility Criteria

Inclusion

  • Spirometry: FEV1/FVC \< 70%; FEV1 between 50 and 80% predicted (GOLD II/III)
  • Clinical Stability (no therapeutic change and/or use of antibiotics) during 8 weeks. - The treatment received will be registered for post-hoc studies stratified by this condition.

Exclusion

  • Drug addiction, alcohol abuse,
  • Use of long-term oral or nebulised antibiotic therapy.
  • History of allergies, asthma or other chronic respiratory disease, sanitary worker, working exposure to dust or fumes.
  • Other diseases: Severe cardiovascular, neurological, psychiatric, renal, hepatic or gastrointestinal , that might interfere with the daily life activities.

Key Trial Info

Start Date :

March 7 2016

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2020

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT03432234

Start Date

March 7 2016

End Date

December 1 2020

Last Update

January 23 2020

Active Locations (6)

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Page 1 of 2 (6 locations)

1

Corporació Sanitaria Parc Tauli

Sabadell, Barcelona, Spain, 08208

2

Hospital Germans Trias i Pujol

Badalona, Spain

3

Hospital Clínic

Barcelona, Spain

4

Hospital de Bellitge

Barcelona, Spain