Status:
COMPLETED
Time-dependent Amiodarone Treatment in Atrial Fibrillation
Lead Sponsor:
Instituto de Cardiología y Medicina Vascular Hospital Zambrano-Hellion Tec Salud
Conditions:
Atrial Fibrillation
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Sixty consecutive emergency patients with newly diagnosed Atrial Fibrillation were randomized into two groups. The first received intravenous amiodarone infusions continuously for 24 hours; the second...
Detailed Description
An open randomized clinical trial was conducted that included 60 emergency adult patients who were candidates for drug cardioversion after first symptomatic episodes of AF. The patients were randomiz...
Eligibility Criteria
Inclusion
- ≥18 years old
- Emergency patients
- First symptomatic episodes of Atrial Fibrillation
Exclusion
- Hemodynamic instability,
- Previous use of antiarrhythmic drugs
- Use of digoxin seven or fewer days prior to the study
- Active thyroid disease
- Known adverse reactions to amiodarone
- Other ventricular arrhythmias
- Contraindications for anticoagulation
- Acute renal failure
- Chronic liver disease
- Transaminase levels that were twice the normal levels
- Acute pulmonary edema
- Uncontrolled hypertension (\> 180/110 mmHg)
- Unstable angina
- Patients who were pregnant and/or breast feeding
Key Trial Info
Start Date :
August 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 30 2009
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT03432663
Start Date
August 1 2008
End Date
November 30 2009
Last Update
February 14 2018
Active Locations (1)
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1
Hospital Universitario "Dr. José Eleuterio González". Universidad Autónoma de Nuevo León
Monterrey, Nuevo León, Mexico, 64460