Status:
UNKNOWN
Advanced Platelet Rich Fibrin in Periodontal Angular Defects
Lead Sponsor:
Alexandria University
Conditions:
Intrabony Periodontal Defect
Eligibility:
All Genders
25-55 years
Phase:
NA
Brief Summary
The aim of this study is to clinically and radiographically evaluate the efficacy of advanced platelet-rich fibrin (A-PRF) when used with biphasic alloplast in the management of intrabony defects in p...
Detailed Description
Biphasic alloplasts have been successfully used in management of intrabony defects. Advanced platelet-rich fibrin is believed to contain higher amount of growth factors and white blood cells than the ...
Eligibility Criteria
Inclusion
- They should be diagnosed as having moderate -severe chronic periodontitis according to the American Academy of Periodontology classification on gingival and periodontal diseases (1999)
- Clinical attachment loss (CAL) ,radiographic evidence of the presence of at least one intrabony defect.
- Patient's age between 25 to 55 years.
- Both sexes.
- No periodontal surgeries in the area of interest during the previous 6 months.
- The presence of intrabony defects (IBD) ≥3 mm deep (distance between alveolar crest and deepest point in the defect estimated from radiographs and confirmed upon surgical exposure).
- An interproximal probing depth (PD) ≥5 mm and clinical attachment loss (CAL) ≥3mm after phase I therapy in maxillary/ mandibular teeth.
- The presence of an adequate zone of keratinized gingiva at the facial aspect of the selected tooth.
Exclusion
- Patients who could not maintain O'leary plaque index (54) ≤10% after phase I therapy.
- Aggressive periodontitis patients.
- Patients with systemic conditions known to affect the periodontal status, or, under medications known to affect the outcomes of periodontal therapy.
- Pregnancy/lactation.
- Smoking and tobacco use in any form.
- Non vital teeth and teeth with grade III mobility.
Key Trial Info
Start Date :
March 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2019
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT03433066
Start Date
March 1 2018
End Date
June 1 2019
Last Update
February 5 2019
Active Locations (1)
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1
Periodontology department, Faculty of Dentistry, Alexandria University
Alexandria, Egypt, 21500