Status:

COMPLETED

OCT Pilot in Esophagus

Lead Sponsor:

Duke University

Collaborating Sponsors:

University of North Carolina, Chapel Hill

National Cancer Institute (NCI)

Conditions:

Barrett Esophagus

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

This is a pilot study to test a newly developed optical coherence tomography (OCT) device to determine 1) whether adequate tissue contact can be attained to acquire high quality images, and 2) to iden...

Eligibility Criteria

Inclusion

  • Presenting to University of North Carolina (UNC) for routine care upper endoscopy
  • Meet one of the following criteria:
  • Presenting to UNC for upper endoscopy of GI conditions without esophageal symptomology for with no history of gastroesophageal reflux disease (GERD) or other esophageal condition affecting the epithelium (asymptomatic controls), OR,
  • History of dysplastic or non-dysplastic Barrett's Esophagus with prague criteria C1+ or M3+
  • Aged 18 to 80
  • Able to read, comprehend, and understand the informed consent document.

Exclusion

  • Prior esophageal surgery (uncomplicated nissen fundoplication OK)
  • Pregnant women
  • Unable to provide written informed consent

Key Trial Info

Start Date :

September 25 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 25 2020

Estimated Enrollment :

53 Patients enrolled

Trial Details

Trial ID

NCT03434834

Start Date

September 25 2018

End Date

March 25 2020

Last Update

April 6 2021

Active Locations (1)

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1

University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, United States, 27599