Status:
UNKNOWN
Regenerative Therapy of Periodontal Bone Defects
Lead Sponsor:
Postgraduate Institute of Dental Sciences Rohtak
Conditions:
Periodontal Bone Loss
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
To compare clinically and radiographically the efficacy of demineralized freeze-dried bone allograft with and without decortication in the treatment of periodontal intrabony defects assessed by gain i...
Detailed Description
INTRODUCTION Periodontitis is a multifactorial infectious disease with microbial plaque as initiator that triggers inflammatory response in the periodontal tissue. As the disease progresses, symptoms ...
Eligibility Criteria
Inclusion
- Age-28-60 years , patients with chronic periodontitis according to criteria of Armitage GC classification system for periodontal diseases and conditions32.
- Presence of 2-, 3-, or combined 2-3-wall intrabony defect ≥ 3 mm deep assessed by transgingival probing and intraoral periapical radiograph, to be confirmed after flap elevation.
- Test tooth and adjoining teeth testing vital, should be free of caries or inadequate restorations.
- Non smokers
- Completed etiological periodontal therapy (oral hygiene instructions and scaling and root-planing with Full-Mouth Bleeding Score FMBS \< 20% and plaque index score\<1 \[Silness and Loe 1964\]33).
- TOOTH OR DEFECT ELIGIBILITY CRITERIA-
- 2-, 3- or combined 2,3-wall intrabony defect.
- Pocket probing depth ≥ 5 mm
- CAL ≥ 5 mm.
- Tooth mobility \< grade 1
Exclusion
- Systemic illness known to affect the periodontium or outcome of periodontal therapy.
- Patient taking medications such as corticosteroids or calcium channel blockers, which are known to interfere periodontal wound healing or patient on long term NSAID therapy.
- Patient allergic to study medications
- Pregnant or lactating mothers.
- Tooth with 1wall intrabony defect.
- Grade2, grade 3 mobile teeth.
- Defects extending to a root furcation area.
- Unrestorable tooth.
- Fractured/perforated roots.
- Developing permanent tooth.
- Endodontically treated tooth.
- Presence of non working interferences.
Key Trial Info
Start Date :
December 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2019
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT03435653
Start Date
December 1 2017
End Date
April 1 2019
Last Update
June 7 2018
Active Locations (1)
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1
Post Graduate Institute of Dental Sciences
Rohtak, Haryana, India, 124001