Status:
UNKNOWN
Evaluation of Safety and Feasibility of EUS-guided RFA for Solid Pancreatic Neoplasms
Lead Sponsor:
Singapore General Hospital
Conditions:
Pancreatic Cancer
Pancreatic Neoplasms
Eligibility:
All Genders
21-99 years
Phase:
NA
Brief Summary
This study aims to evaluate the safety and efficacy of new ablation catheter developed by MEDICAL TAEWOONG for the treatment of pancreatic neoplasm (pancreatic adenocarcinoma or neuroendocrine tumour)...
Detailed Description
RFA causes tissue destruction through the application of a high frequency alternating current, generating local temperatures above 60°C and leading to coagulative necrosis. The technique has been wide...
Eligibility Criteria
Inclusion
- Age 21 years-old or above
- Suffering from pancreatic neuroendocrine tumour or pancreatic ductal carcinoma that was confirmed by fine needle aspiration cytology
- Unsuitable for surgery, due to one (or more) of the following items:
- ASA score \>/= III
- An alternative advanced malignancy
- Unsuitable for surgery upon expert's opinion for any other reason
- Individuals who are not keen for surgical resection
- Eligible for endoscopic intervention
- Written informed consent
Exclusion
- Coagulopathy (international normalized ratio \>1.5, partial thromboplastin time greater than twice that of control), platelet count \<50,000x103/uL
- Pregnancy
- Patients with a poor mental condition or mental retardation, unable to understand the nature and possible consequences of the study
- Patients unwilling to undergo follow-up assessments
- Patients with liver cirrhosis, portal hypertension and/or gastric varices.
Key Trial Info
Start Date :
March 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2019
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT03435770
Start Date
March 1 2018
End Date
September 1 2019
Last Update
February 20 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Singapore General Hospital
Singapore, Singapore, 169856