Status:
UNKNOWN
Tissue-specific Effects of Insufficient Sleep
Lead Sponsor:
University of Colorado, Denver
Conditions:
Healthy
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
This study plans to learn more about how sleep loss impacts the way the body responds to sugar. This work will have important implications for development of treatments and countermeasures for people ...
Detailed Description
Participants will stay in the hospital for 6 days and will not be able to leave. Sleep habits will be measured for 7 days before the study. A research diet that is designed to maintain weight will be ...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Healthy, lean participants.
- No regular physical activity (\<20 minutes/day). No exercise will be allowed for 3 days prior to study start.
- Habitual sleep duration between 7-9.25h. Subjects must also be willing and able to keep a 9h time-in-bed schedule for 1 week prior to study admission.
- Potential subjects must have lived at Denver altitude or higher for at least 3 months to inpatient study.
- Exclusion Criteria:
- Current or history of any clinically significant medical, psychiatric, or sleep disorder.
- Use or history of any drugs, medications, supplements, caffeine, and alcohol.
- Current or history of shiftwork in six months prior to laboratory study.
- Travel more than one time zone in three weeks prior to laboratory study.
- Blood donation in the 30 days prior to inpatient study.
Exclusion
Key Trial Info
Start Date :
February 12 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 30 2024
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT03437681
Start Date
February 12 2018
End Date
December 30 2024
Last Update
November 30 2023
Active Locations (1)
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1
University of Colorado Anschutz Medical Campus
Aurora, Colorado, United States, 80045