Status:
TERMINATED
Resistance STEMI Study
Lead Sponsor:
Catharina Ziekenhuis Eindhoven
Conditions:
STEMI
Acute Myocardial Infarction
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
In acute myocardial infarction, early restoration of blood flow to the jeopardized myocardium is of paramount importance to limit infarct size and to improve long term outcome. Primary percutaneous co...
Eligibility Criteria
Inclusion
- Age between 18 and 75 years
- Presentation within 12 hours after the onset of complaints
- Acute ST-elevation myocardial infarction with a total ST segment deviation ≥5 mm
- Able to give and understand informed consent
- Culprit lesion in a proximal or mid-segment of one of the major coronary arteries (diameter ≥2,5 mm), which is stented successfully
- Stable condition after stenting
- One or more additional lesions in one or more different coronary arteries, mandating FFR measurement +/- PPCI during the subacute phase
Exclusion
- Age \< 18 years or \> 75 years
- Cardiogenic shock or pre-shock, determined by the clinician
- Patients with previous myocardial infarction in the culprit artery or with previous bypass surgery
- Very tortuous or calcified coronary arteries
- Long or complex PPCI
- Severe concomitant disease or conditions with a life expectancy of less than 1 year
- Inability to understand and give informed consent
- Known myocardial diseases such as severe left ventricular hypertrophy or cardiomyopathy
- Pregnancy
- Severe conduction disturbances necessitating implantation of a temporary pacemaker
- Contraindications for MRI (claustrophobia, ferromagnetic metal fragments in the body)
Key Trial Info
Start Date :
October 15 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2019
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT03439150
Start Date
October 15 2018
End Date
July 1 2019
Last Update
July 16 2020
Active Locations (1)
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1
Catharina Hospital
Eindhoven, North Brabant, Netherlands, 5623EJ