Status:
UNKNOWN
Dynamic Measurement of Renal Functional Reserve as a Predictor of Long-Term Renal Function
Lead Sponsor:
Thomas Mueller
Conditions:
Adult Polycystic Kidney Disease
Kidney Neoplasms
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The number of people with kidney disease is constantly rising and renal failure represents one of the major health care burdens globally. An accurate measurement of kidney function is urgently needed ...
Detailed Description
The measurement of RFR will be performed by dynamic testing of the changes in baseline glomerular filtration rate (GFR) induced by an oral protein load. Sinistrin (a polyfructosan with identical clear...
Eligibility Criteria
Inclusion
- Potential living kidney donor
- Patients with diagnosed ADPKD
- Patients with primary kidney tumor requiring nephrectomy
- Female and male patients over 18 years of age
Exclusion
- Bilateral kidney tumor
- Kidney metastases of a tumor of other origin
- Renal failure that requires dialysis
- Pregnant patient
- Incomplete medical records
- Patients with diabetes mellitus
- Patients who cannot tolerate iv fluids
- Hypersensitivity to the active substance (sinistrin) or to any of the excipients
Key Trial Info
Start Date :
June 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 30 2019
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03442647
Start Date
June 1 2018
End Date
August 30 2019
Last Update
May 14 2018
Active Locations (1)
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1
University Hospital Zurich
Zurich, Switzerland, 8091