Status:
UNKNOWN
Propofol Target-Controlled Infusion in Emergency Department Sedation
Lead Sponsor:
NHS Greater Glasgow and Clyde
Collaborating Sponsors:
C. R. Bard
Conditions:
Shoulder Dislocation
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
There exists continued controversy over the use of propofol in Emergency Department procedural sedation, this is despite its widespread existence in clinical practice for at least a decade. These conc...
Detailed Description
Procedural sedation and analgesia (PSA) has long been a core skill of the Emergency Physician, although over the last decade, developments in patient monitoring and the use of newer sedative and analg...
Eligibility Criteria
Inclusion
- Aged 18-65 years
- Clinical and/or radiological evidence of acute anterior shoulder dislocation
- ASA I or II
- Fasted ≥ 90mins2,3,27,28
- Weight ≥50kg
Exclusion
- Inability to provide or refusal of informed consent
- Previous attempt at reduction during the same presentation
- Previously enrolled in the study
- Clinical and/or radiological evidence of acute posterior shoulder dislocation
- Clinical and/or radiological evidence of concomitant ipsilateral upper limb fracture (with the exception of an isolated avulsion fracture of the greater tuberosity or a fracture of the glenoid labrum)
- Concomitant multi-system injury
- History of difficult intubation/airway surgery
- ASA grade III, IV or V
- Haemodynamic instability
- Pregnancy
- Contraindication to sedation
- Allergy to study drugs or eggs
- Clinician decision
- Morphine administration within the preceding 20minutes prior to starting TCI (can be included if \>20minutes)
Key Trial Info
Start Date :
April 3 2017
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2018
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03442803
Start Date
April 3 2017
End Date
December 31 2018
Last Update
February 22 2018
Active Locations (4)
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1
Glasgow Royal Infirmary
Glasgow, United Kingdom, G4 0SF
2
Queen Elizabeth University Hospital
Glasgow, United Kingdom, G51 4TF
3
Hairmyres Hospital
Glasgow, United Kingdom, G75 8RG
4
Royal Alexandra Hospital
Paisley, United Kingdom, PA2 9PN