Status:

UNKNOWN

Effect of Exenatide LAR or Dulaglutide on the Variability of 24-hour Heart Rate and Blood Pressure in Type 2 Diabetes

Lead Sponsor:

University of Guadalajara

Conditions:

Diabetes Mellitus, Type 2

Eligibility:

All Genders

31-60 years

Phase:

PHASE4

Brief Summary

Mortality due to cardiovascular problems is increased by having Diabetes Mellitus type 2 (DM2), related to the time of evolution and glucose levels or if alterations in blood pressure coexist. With th...

Detailed Description

A randomized, open clinical trial of 30 patients with a diagnosis of diabetes in accordance with the American Diabetes Association (ADA) without treatment. They will be assigned randomly in two group...

Eligibility Criteria

Inclusion

  • Patients both sexes
  • Age between 31 and 60 years
  • Diagnosis of diabetes according ADA criteria:
  • (Fasting blood glucose levels \>125 mg/dl or postprandial blood glucose levels after an oral glucose tolerance test with 75 of oral glucose \> 200 mg/dl, or glycosylated hemoglobin \>6.5%).
  • • Informed consent signed

Exclusion

  • Women with confirmed or suspected pregnancy
  • Women under lactation and/or puerperium
  • Hypersensibility to ingredients of intervention
  • Physical impossibility for apply the drug
  • Known pancreatic, renal, hepatic, heart or thyroid diseased
  • Hypertension diagnosis
  • Previous treatment for glucose
  • Body Mass Index ≥39.9 kg/m2
  • Triglycerides ≥500 mg/dL
  • Total cholesterol ≥300 mg/dL
  • Night or rotating shift workers
  • Blood Pressure ≥140/90 mmHg

Key Trial Info

Start Date :

November 17 2017

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 30 2021

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT03444142

Start Date

November 17 2017

End Date

November 30 2021

Last Update

March 26 2020

Active Locations (1)

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Instituto de terapeutica Experimental y Clinica. Centro universitario de Ciencias de la Salud. Universidad de Guadalajara

Guadalajara, Jalisco, Mexico, 44340