Status:
WITHDRAWN
Parabens Flocculation on the Anti Inflammatory Effects of Corticosteroid Injections for Total Knee Arthroplasty
Lead Sponsor:
Loma Linda University
Conditions:
Osteoarthritis, Knee
Eligibility:
All Genders
19-89 years
Phase:
EARLY_PHASE1
Brief Summary
The purpose of this study is to identify whether corticosteroid use with anesthetics containing preservatives (parabens) reduces clinical effectiveness of the anti-inflammatory agent Up to 100 patient...
Detailed Description
Corticosteroid injections have been used to treat inflammatory conditions for many decades (Storz 1973; Roszental, Zurakowski and Blazar 2008). In order to maximize the effectiveness on the synovial t...
Eligibility Criteria
Inclusion
- Diagnosis of symptomatic primary knee osteoarthritis according to the American Rheumatism Association classification criteria for knee osteoarthritis, ability to understand study protocol and agreement to participate
Exclusion
- History of any knee injection in the past 6 months, History of more than 2 injections in the knee under study, previous fracture or surgical procedure of knee under investigation, any benign or malignant tumor in knee, chemotherapy, hemearthosis, current infection in the affected limb.
Key Trial Info
Start Date :
September 15 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 30 2019
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT03445611
Start Date
September 15 2019
End Date
October 30 2019
Last Update
June 3 2021
Active Locations (1)
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1
Loma Linda University Health, Department of Orthopaedic Surgery
Loma Linda, California, United States, 92354