Status:
COMPLETED
68 Ga-NODAGA-E[c(RGDγK)]2: Positron Emission Tomography Tracer for Imaging of Myocardial Angiogenesis
Lead Sponsor:
Rigshospitalet, Denmark
Conditions:
Acute Myocardial Infarction
Eligibility:
All Genders
50+ years
Phase:
PHASE2
Brief Summary
The aim is to examine the expression of αvβ3 integrin using a novel selective radiotracer in patients with myocardial infarction and investigate if it is a suitable tool for predicting myocardial reco...
Detailed Description
Ischemic heart disease is worldwide the single most frequent cause of death. The number of patients surviving acute myocardial injury is increasing due to improved acute treatment. However, after the ...
Eligibility Criteria
Inclusion
- Age over 50 years
- Acute myocardial infarction Group:
- Verified first-time acute myocardial infarction treated with PCI
- Control Group:
- Previous healthy
- No known cardiac disease
Exclusion
- No prior history of acute coronary infarction
- No prior history of Heart surgery
- Not treated with anti-angiogenic medicine
- Subject with pacemaker, cochlear implant or insulin pump
- Pregnancy
- Lactation
- Severe claustrophobia
- Severe obesity (weight above 140kg)
- If a subject is in the fertile age, a pregnancy test will be use prior to injection to the PET\_tracer
- If a subject is having a severe allergic reaction to the PET-tracer, the person will be excluded for the rest of the trial
- If the PET-tracer is administered subcutaneous, the person will be excluded for the rest of the trial¨
- Tupe I or II diabetes
Key Trial Info
Start Date :
February 20 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2020
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT03445884
Start Date
February 20 2018
End Date
July 1 2020
Last Update
July 14 2020
Active Locations (1)
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1
Department of Physiology, Nuclear Medicine and PET
Copenhagen, Capital Region, Denmark, 2100