Status:
UNKNOWN
The Role of Consumption and Anticipation in Dopamine Release to Food Reward
Lead Sponsor:
Universitaire Ziekenhuizen KU Leuven
Conditions:
Healthy
Food Reward
Eligibility:
FEMALE
18-50 years
Phase:
NA
Brief Summary
This study aims to disentangle the relative contribution of the anticipatory (food images) versus consummatory (food administration) component of dopamine release to food reward, by performing simulta...
Detailed Description
The brain's reward system has a potent contribution to the regulation of food intake. Although animal work has demonstrated a key role of the mesolimbic dopamine system in food reward responses, evide...
Eligibility Criteria
Inclusion
- Healthy females (on hormonal contraception)
- Dutch-speaking
- Right-handed
- Stable body weight with Body Mass Index (BMI) of 18.5 - 25 kg/m\^2
Exclusion
- Medical, neurological or psychiatric disorders
- Use of psychotropic medication in past 6 months
- Use of cannabis or other drugs of abuse in past 12 months
- Lactose-intolerance or food allergies
- Vegetarian diet
- Smoking
- Consumption of more than 7 alcoholic units per week
- Exposure to a significant amount of ionizing radiation in past 12 months
- Claustrophobia
- Contra-indications for Magnetic Resonance Imaging
- Pregnancy
Key Trial Info
Start Date :
February 8 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2019
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT03447561
Start Date
February 8 2018
End Date
June 1 2019
Last Update
February 27 2018
Active Locations (1)
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1
Universitaire ziekenhuizen Leuven
Leuven, Belgium, 3000