Status:

COMPLETED

Plasma Dihydroceramides Are Associated With Hepatic Steatosis in Type 1 and Type 2 Diabetes

Lead Sponsor:

Groupe Hospitalier Pitie-Salpetriere

Conditions:

Diabetes Mellitus, Type 2

Diabetes Mellitus, Type 1

Eligibility:

All Genders

18-75 years

Brief Summary

Sphingolipids are associated with metabolic diseases. Distribution of plasma sphingolipids in type 1 and type 2 diabetes has never been studied. The objective of the CERADIAB study is to compare plasm...

Detailed Description

Sphingolipids represent a major class of lipids that are structural and signaling molecules. Major bioactive sphingolipids include ceramide, dihydroceramide, sphingosine, sphingosine-1-phosphate and s...

Eligibility Criteria

Inclusion

  • type 1 or 2 diabetes

Exclusion

  • atypical diabetes
  • family dyslipidemia
  • nonmetabolic hepatopathy
  • severe renal failure
  • corticosteroid or immunosuppressive therapy

Key Trial Info

Start Date :

April 4 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 16 2017

Estimated Enrollment :

128 Patients enrolled

Trial Details

Trial ID

NCT03447964

Start Date

April 4 2017

End Date

September 16 2017

Last Update

October 18 2018

Active Locations (1)

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1

Groupe Hospitalier Pitié-Salpêtrière

Paris, France, 75013