Status:
COMPLETED
Perioperative Ketamine for Pain With Gastric Bypass
Lead Sponsor:
Mayo Clinic
Conditions:
Laparoscopic Gastric Bypass Surgery
Ketamine
Eligibility:
All Genders
18-69 years
Phase:
PHASE2
Brief Summary
Opioid medications such as morphine, hydrocodone and oxycodone are standard for treating pain after surgery, however there are disadvantages. Because of the way opioids work, gastric bypass patients m...
Eligibility Criteria
Inclusion
- Patients undergoing laparoscopic gastric bypass at Mayo Clinic in Arizona
- BMI is ≥ 35 kg/m2
- Consent is able to be obtained as per Mayo Clinic policy
Exclusion
- Intolerance to ketamine
- History of schizophrenia, schizoaffective disorder, or other psychiatric diagnosis with psychotic features
- Presence of unstable cardiovascular disease (presence of acute coronary syndrome, unstable angina, hypertension emergency, acute transient ischemic attack (TIA) or stroke)
- Presence of acute elevation of intracranial or intraocular pressure
- Presence of seizure disorder
- History of substance abuse or addiction
- Creatinine greater than 1.5 mg/dL
- End-stage liver disease
- Pregnancy
- Patients with chronic pain and/or chronic opioid therapy will not be excluded to more closely replicate the study patient population of interest. However, patients taking greater than 50 morphine equivalents (ME) per day for greater than 1 month prior to surgery will be excluded.
Key Trial Info
Start Date :
April 16 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 9 2020
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT03448068
Start Date
April 16 2018
End Date
January 9 2020
Last Update
April 29 2021
Active Locations (1)
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1
Mayo Clinic in Arizona
Phoenix, Arizona, United States, 85054