Status:
TERMINATED
Opening Wedge High Tibial Osteotomy
Lead Sponsor:
Kuopio University Hospital
Collaborating Sponsors:
Central Finland Hospital District
Conditions:
Osteoarthrosis of Knee
Osteoarthritis, Knee
Eligibility:
All Genders
25-55 years
Phase:
NA
Brief Summary
A prospective, randomised controlled trial where clinical and radiological outcome of high tibial opening wedge osteotomy with physiotherapy is compared to physiotherapy alone while treating symptomat...
Detailed Description
90 Symptomatic patients with mild to moderate medial knee osteoarthrosis are randomized to two groups: Group 1 (HTO-group) receive an diagnostic arthroscopy with high tibial opening wedge osteotomy (...
Eligibility Criteria
Inclusion
- Pain: Subjective pain in the knee most of the month for at least one month during past 12 months.
- Knee range of motion (ROM) at least 5-120 degrees
- X-ray: medial joint space Altman \> 1. Lateral joint space Altman \< 2.
- Mechanical axis \> 3 degrees varus alignment.
- Medial proximal tibial angle (MPTA) \< 90 degrees
- age 25-55.
- Written consent, accepts both treatment arms.
Exclusion
- Pain is caused by something else than medial knee osteoarthrosis
- deficient ROM (flexion contracture \> 10 degrees, flexion \< 110 degrees)
- significant ligament instability
- post traumatic OA
- clinically relevant neurological disease (e.g. Alzheimer´s disease)
- clinically relevant metabolical disease (e.g. Diabetes)
- alcohol/drug abuse
- infectious/inflammatory joint disease
- previous knee area osteotomy or lower limb arthroplasty
- smoking (\> 0 cigarette per day)
- obesity (BMI \> 33)
- pregnancy or hope of pregnancy in the following two years
Key Trial Info
Start Date :
May 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 10 2023
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT03448796
Start Date
May 1 2018
End Date
May 10 2023
Last Update
October 27 2023
Active Locations (1)
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1
University Hospital of Kuopio
Kuopio, Finland