Status:

COMPLETED

Optimizing and Individualizing the Pharmacological Treatment of First-episode Schizophrenic Patients

Lead Sponsor:

Central South University

Collaborating Sponsors:

Xiangya Hospital of Central South University

Shanghai Mental Health Center

Conditions:

Schizophrenia

Metabolic Syndrome

Eligibility:

All Genders

17-65 years

Brief Summary

The study is performed in 20 different hospitals from 19 cities in China. Three sub-projects are included. About sub-project 1, we build a clinical database system and a biological sample bank for dat...

Detailed Description

For sub-project1 and 2:Inclusion criteria: Participants are ineligible to enter the trial under the following conditions: 1) Participants must be aged 18 to 65 years old who meet the criteria for schi...

Eligibility Criteria

Inclusion

  • Meet the Diagnostic and Statistical Manual (DSM-V) diagnostic criteria for schizophrenia;
  • Duration of illness less than 3 years with current symptoms exacerbation;
  • Male and female with aged 17 to 65 years;
  • Signed the study consent for participation

Exclusion

  • Having history of substance dependence or abuse or whose symptoms are caused by the other diagnosable mental disorders;
  • Having history of traumatic brain injury, seizures or other known neurological or organic diseases of the central nervous system;
  • Taking antidepressants, stimulants, mood stabilizer or accepts electricity shock treatment;
  • Having current suicidal or homicidal thoughts or any safety concern by research staff that cannot be manage in an inpatient setting;
  • The routine blood tests showing abnormal renal, liver function;
  • Pregnant or lactating women.
  • No administration of any antibiotics in a mouth

Key Trial Info

Start Date :

January 23 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 30 2021

Estimated Enrollment :

2000 Patients enrolled

Trial Details

Trial ID

NCT03451734

Start Date

January 23 2018

End Date

June 30 2021

Last Update

August 12 2021

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Mental Health Institute of 2nd Xiangya Hospital,CSU

Changsha, Hunan, China, 410011