Status:
COMPLETED
The Effect of an Antibiotic on the Production of Uremic Toxins by the Gut Microbiome
Lead Sponsor:
NYU Langone Health
Conditions:
End Stage Renal Disease
Eligibility:
All Genders
18-80 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to determine if multiple doses of vancomycin over the course of 3 months will perturb the intestinal flora (microbiome) and result in reduced serum concentration of the ur...
Eligibility Criteria
Inclusion
- Patients with stable chronic kidney disease on hemodialysis with a fistula or an AV graft.
Exclusion
- Antibiotics received within the last 3 months;
- recent diarrhea
- known allergy to vancomycin
- history of C. difficile infection
- elevation of white blood cell count or fever within one week of enrollment.
Key Trial Info
Start Date :
November 27 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 18 2018
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT03452189
Start Date
November 27 2017
End Date
August 18 2018
Last Update
March 26 2021
Active Locations (1)
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1
New York University School of Medicine
New York, New York, United States, 10016