Status:
COMPLETED
Epigenomic and Metabolomic Signatures of APOA2 Gene by Saturated Fat Interaction
Lead Sponsor:
Tufts University
Conditions:
Body Mass Index
Eligibility:
All Genders
18-90 years
Brief Summary
Obesity is driven by genetic and environmental factors. Among the latter, diet is a most important one. The investigators refer to these combinations of genetic and dietary factors as 'gene-diet inter...
Detailed Description
Background: Apolipoprotein A-II (APOA2) is a significant constituent of high-density lipoproteins (HDL) with an undefined biological role. A putative functional variant, -265 T\>C (rs5082) within the ...
Eligibility Criteria
Inclusion
- subjects with the apoA2 genotype TT or CC
Exclusion
- all other genotypes
Key Trial Info
Start Date :
January 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2017
Estimated Enrollment :
602 Patients enrolled
Trial Details
Trial ID
NCT03452787
Start Date
January 1 2017
End Date
December 31 2017
Last Update
March 2 2018
Active Locations (1)
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1
JM-USDA-HNRCA at Tufts University
Boston, Massachusetts, United States, 02111