Status:
UNKNOWN
Spastic Cocontractions and Limitation of Active Movements Before and After Treatment During Injection of Botulinum Toxin
Lead Sponsor:
University Hospital, Toulouse
Conditions:
Cerebrovascular Accident
Stroke
Eligibility:
All Genders
18+ years
Brief Summary
Following a stroke , 55% of the patients do not recover any traction of the upper limb and 30% a residual motricity not allowing a functional grip. For this last group of patients, there are major the...
Detailed Description
Descriptive study of spastic cocontraction index before and after botulinum toxin A injections during active elbow extension in chronic vascular hemiplegic patients. The spastic cocontraction score w...
Eligibility Criteria
Inclusion
- Having notified his non-opposition to participate in the search
- Ischemic or hemorrhagic stroke of more than 6 months, cortical and / or subcortical;
- Indication to the realization of an injection of Botulinum Toxin A in the flexor muscles of the elbow according to the usual clinical criteria: presence of a functional complaint or aesthetic expressed by the patient and related to hyperactivity muscular (spasticity or cocontraction) on the flexor muscles elbow, which is a focal treatment by injection of botulinum toxin;
- Possibility of active extension of elbow\> 20 °;
- Patients naive to Botulinum Toxin A or more than 4 months of a first injection of Botulinum Toxin A, having targeted the elbow flexors.
Exclusion
- Passive limitation of elbow extension\> 30 °;
- Pain when performing active movements of flexion / extension of the elbow
- Cognitive impairment limiting the comprehension of three basic instructions (proof test of the 3 papers of the MMS);
- Evolutionary or decompensated neurological pathology; Ischemic or haemorrhagic stroke of less than 6 months;
- General contraindication to the production of botulinum toxin; history of myasthenia gravis, Lambert Eaton syndrome; history of neuromuscular disease; surgery with curarization for less than 1 month; treatment with aminoglycoside, aminoquinoline or cyclosporine
- Legal incapacity (safeguard of justice, guardianship).
Key Trial Info
Start Date :
January 14 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2019
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03453008
Start Date
January 14 2018
End Date
September 1 2019
Last Update
March 5 2018
Active Locations (1)
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1
University Hospital Toulouse
Toulouse, France, 31052