Status:
UNKNOWN
A Comparative Study of Different Hypothermic Circulatory Arrest Strategies on Aortic Surgery.
Lead Sponsor:
Xiaoping Fan. MD
Collaborating Sponsors:
Jie He.MD
Shihao Cai.MD
Conditions:
Morality
Hypothermic Circulatory Arrest Time
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
By comparing the clinical outcome of patients underwent different hypothermic circulatory arrest (mild hypothermic versus moderate hypothermic) during aortic arch surgery, this study aims to determine...
Detailed Description
Hypothermic circulatory arrest (HCA) is the cornerstone of aortic surgery. It provides a bloodless and still operative field. But the side effect of hypothermia also draws people's concern. With the d...
Eligibility Criteria
Inclusion
- Patients with confirmed diagnosis (i.e.aortic dissection, marfan syndrome, aortic arch aneurysm and so on), which require total aortic arch replacement.
Exclusion
- Preoperative heart attack or coma.
- Patients with surgical contraindication, including but not limited to severe cardiac,pulmonary,renal or hepatic insufficiency.
- Pre-existing heart condition or neurological disease.
- Variation of aortic arch or its branch vessels.
- Patient is currently on anticoagulation therapy or has other medical condition that compromises the coagulation.
- Patient with active infection.
- Allergy to anaesthetic or contrast agent.
- Pregnant or lactating female.
- Patient is already on other medical trial.
- Other medical, psychological or socioeconomics condition determined by investigator that is not eligible for the study.
Key Trial Info
Start Date :
August 3 2018
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 15 2020
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT03454633
Start Date
August 3 2018
End Date
December 15 2020
Last Update
August 6 2018
Active Locations (1)
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1
Guangdong General Hospital
Guangzhou, Guangdong, China, 510080