Status:

COMPLETED

Dynamic Arterial Elastance Measured by Uncalibrated Pulse Contour Analysis Predicts Arterial Pressure Response to a Decrease in Norepinephrine

Lead Sponsor:

Centre Hospitalier Universitaire, Amiens

Conditions:

Vasoplegia Syndrome

Eligibility:

All Genders

18+ years

Brief Summary

Dynamic arterial elastance (Eadyn) has been proposed as an indicator of arterial tone that can predict norepinephrine-dependent arterial pressure. Eadyn is calculated using the ratio of respiratory pu...

Detailed Description

* Background : Dynamic arterial elastance (Eadyn) has been proposed as an indicator of arterial tone that can predict norepinephrine-dependent arterial pressure. Eadyn is calculated using the ratio of...

Eligibility Criteria

Inclusion

  • Inclusion criteria were all consecutive patients with a diagnosis of vasoplegic syndrome, treated with norepinephrine, for whom the attending physician decided to decrease the norepinephrine dosage. The vasoplegic syndrome was defined as persistent arterial hypotension with normal or high cardiac output and low systemic vascular resistance

Exclusion

  • Exclusion criteria were patients treated with epinephrine and/or dobutamine, arrhythmia, intra-abdominal hypertension and patients younger than 18 years.

Key Trial Info

Start Date :

October 11 2016

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 26 2017

Estimated Enrollment :

35 Patients enrolled

Trial Details

Trial ID

NCT03455738

Start Date

October 11 2016

End Date

April 26 2017

Last Update

September 28 2018

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