Status:

TERMINATED

A Prospective Cohort Study:Forecast Fracture Risk With a Serum Marker of Type 2 Diabetes in Guangzhou Community

Lead Sponsor:

Zhujiang Hospital

Conditions:

Type 2 Diabetes Mellitus and Fragility Fractures

Eligibility:

All Genders

18-65 years

Brief Summary

The objective of this study is to find out the biochemical markers which have independent predictive value of fragility fractures risk with Type 2 diabetes in Guangzhou community and evaluate bone str...

Eligibility Criteria

Inclusion

  • (1) aged 18-65 years; (2) patients were diagnosed with type 2 diabetes based on the definition of diabetes of WHO in 1999.

Exclusion

  • 1\. type 1 diabetes and other specific types of diabetes; 2. diabetes related acute complications like diabetic ketoacidosis and hyperglycemic hyperosmolar status. 3. had used drugs that is known to have effect on bone(like active vitamin D, bisphosphonate, calcitonin, estrogen receptor modulators, estrogen, thiazolidinediones); 4. suffer from diseases that is known to have effect on bone (hyperthyroidism, hypothyroidism, hyperparathyroidism, hypoparathyroidism,cushing syndrome,chronic renal failure,renal tubular acidosis,osteoporosis after gastrectomy,osteoporosis caused by liver disease,rheumatoid disease,osteoporosis induced by gastrointestinal absorption dysfunction); 5. disuse osteoporosis; 6. cannot be exposure to sunlight due to skin diseases; 7. use glucocorticoids for over 3 months.

Key Trial Info

Start Date :

July 1 2017

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2021

Estimated Enrollment :

99 Patients enrolled

Trial Details

Trial ID

NCT03456271

Start Date

July 1 2017

End Date

December 31 2021

Last Update

March 21 2022

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Baiyun Community Taihe Town

Guangzhou, Guangdong, China, 510000

2

Guangzhou No.12 People's Hospital

Guangzhou, Guangdong, China, 510000

3

Haizhu Changgang Community

Guangzhou, Guangdong, China, 510000

4

Tianhe Community

Guangzhou, Guangdong, China, 510000