Status:
COMPLETED
Pattern of Acute on Chronic Liver Failure in Patient With HCV Related Chronic Liver Disease
Lead Sponsor:
Assiut University
Conditions:
Acute-On-Chronic Liver Failure
Eligibility:
All Genders
18+ years
Brief Summary
The concept of acute-on-chronic liver failure (ACLF) was introduced by Jalan and Williams in 2002 to describe the acute deterioration in liver function over 2 to 4 weeks in a patient with well-compens...
Detailed Description
There may be regional differences in etiology, pathogenesis, and natural course of ACLF, which may in turn influence the overall outcome of this syndrome. So, proper diagnosis of ACLF and its precipit...
Eligibility Criteria
Inclusion
- Adult Patients with HCV related CLD based on clinical, biochemical and imaging evidence., with or without prior decompensation.
- Patients diagnosed to have ACLIF at any grade (1-3)
Exclusion
- Acute liver failure without evidence of chronic liver disease.
- Other etiology of chronic liver disease
- Patients diagnosed with no ACLIF No ACLF
- This category includes patients who either:
- Do not have any organ failure
- Have a single organ failure that does not involve the kidney with a serum creatinine level of \<1.5 mg per dl and no hepatic encephalopathy
- Have a single brain failure with a serum creatinine level of \<1.5 mg per dl
- Patients refuse to participate.
Key Trial Info
Start Date :
November 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 30 2019
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT03456518
Start Date
November 1 2018
End Date
November 30 2019
Last Update
January 23 2020
Active Locations (2)
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1
Al-Rajhi Liver Hospital, Assiut University
Asyut, Egypt, 71515
2
Al-Rajhi liver hospital ,Assiut university
Asyut, Egypt