Status:
UNKNOWN
The Canadian Glomerulonephritis Registry and Translational Research Initiative
Lead Sponsor:
University Health Network, Toronto
Collaborating Sponsors:
Sunnybrook Health Sciences Centre
Providence Health & Services
Conditions:
Glomerular Nephritis
Eligibility:
All Genders
18-80 years
Brief Summary
Glomerulonephritis (GN) is one of the most important causes of kidney failure in Canada. These comprise a group of "rare" diseases (\<5 per 250,000 population), yet GN is a leading cause of kidney fai...
Detailed Description
To accomplish the goals set out in this project, the CGNR network will recruit and maintain a large cohort of patients 350 with glomerular diseases and follow them prospectively with standardized clin...
Eligibility Criteria
Inclusion
- diagnosis of IgAN, FSGS, MCD, MGN, MPGN
- age 18-80 inclusive
- estimated GFR\>=30ml/min/1.73m2 estimated using 4 variable MDRD
- first kidney biopsy within 12 months of enrollment
- connective tissue disease serology is normal/negative ANA, ANCA
Exclusion
- Systemic lupus erythematosus (SLE) - serology supported
- Evidence of diabetic nephropathy on renal biopsy
- Underlying connective tissue disease and/or serologic evidence (sarcoid, rheumatoid arthritis, vasculitis)
- Prior organ transplant
Key Trial Info
Start Date :
October 19 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 30 2023
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT03460054
Start Date
October 19 2017
End Date
June 30 2023
Last Update
March 9 2018
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Health Network
Toronto, Ontario, Canada, M5G2C4