Status:
UNKNOWN
Evaluation of Clinical and Genetic Modifiers of Long-term Survival in Heart Failure
Lead Sponsor:
Tongji Hospital
Conditions:
Heart Failure
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to evaluate the beta-adrenergic receptor gene polymorphisms in the long-term effects of beta-blockade in patients with chronic heart failure.
Eligibility Criteria
Inclusion
- 18 years of age or older;
- Patients are required to have chronic heart failure (NYHA II-IV) with a left ventricular ejection fraction lower than 40%;
- Patients are voluntary and signed informed consent.
Exclusion
- Pregnant women or plan to;
- Participate in any drug clinical trials within 3 months;
- Serious neurological disease (Alzheimer's disease, Parkinson syndrome, progressive lower limbs or deaf patients);
- Previous history of cancer or tumor, or pathological examination confirmed precancerous lesions;
- Patients refused to comply with the requirements of this study to complete the research work;
- According to the researchers, patients can not complete the study or not to comply with the requirements of this study (because of the reasons for the management or other reasons).
Key Trial Info
Start Date :
April 18 2016
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2020
Estimated Enrollment :
2500 Patients enrolled
Trial Details
Trial ID
NCT03461107
Start Date
April 18 2016
End Date
December 31 2020
Last Update
April 10 2019
Active Locations (1)
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1
Tongji Hospital
Wuhan, Hubei, China, 430030